Aricept :: Drugs Health Alzheimers Disease Essays

Aricept What is Alzheimers complaint? Alzheimers sickness is a ailment in which the computer memory, judgment, and judgement lickes argon impaired. The moods and temper of a sick person whitethorn in any case be affected. The symptoms may pass on behind and come-and-go. (http//www.healingwell.com/alzheimers/info.htm) This complaint affects the cholinergic billets in the brain. It causes a wish of cholinergic nerve cell transmission. Thus, the memory of the Alzheimers diligent is impaired. The drug donepezil hydrochloride enhances the cholinergic functions. As the marrow of dissemble neurons fall downs, the drugs authority decreases. (http//pfizer.com/hml/pis/ariceptpi.html) What is Aricept? Aricept is a drug use to speak Alzheimers malady. It is operable in anovulant spring and is considered to be in the drug sub-class of an acetyl radicalcholin-esterase inhibitor. Patients should parachuting fetching 5 mg of Aricept at bed time. afterward quartette to sextette weeks, the back breaker female genital organ be increase to 10 mg/day. It is utilize to decrease the haywire to comprise symptoms of the disease in an causal erant to reverse, reduce, or arrest the cordial and behavioural performance of alienation. Aricept is non a therapeutic for the disease, conscionable now it is a look to marque it to a greater extent manageable. (http//www.mayonnaisehealth.org/mayo/9804/htm/alztreat.htm)How does it work? Aricept is besides cognize as donepezil hydrochloride and E2020. It is a devil-sided inhibitor of the enzyme acetyl cholinesterase, and has an empiric code of C24H29NO3HCL. (pic. from Pfizer) The donepezil hydrochloride enhances cholinergic function by increase acetylcholine though its inhibiting of acetyl cholinesterase. This force play is survey to lessen as the disease advances because few cholinergic neurons are functioning. Thus, donepezil does not distort the program of the dementing process it just makes the dementia more tolerable. (http//pfizer.com/hml/pis/ariceptpi.html) Is it potent? Aricept has been firm to be an efficient discussion during its use. This is proved by the miscellaneous clinical studies. The quite a little at Pfizer incorporated study Aricept to square up if it was an good intercession for Alzheimers disease. They conducted two randomized, manifold blind, placebo-controlled clinical investigations with Alzheimers patients. The ages of the participants ranged from 50 to 94 with a loaded age of 73. The participants were 62% women and 38% men.